APA
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Vigneault, A., Mylniczenko, N., Arnold, R., Jasper-Trotter, S. L., Summa, N. M., Rousseau, C., & Vergneau-Grosset, C. (2023). MANAGEMENT OF SUSPECTED DILATED CARDIOMYOPATHY WITH PIMOBENDAN IN TWO LEOPARD SHARKS (TRIAKIS SEMIFASCIATA). Journal of Zoo and Wildlife Medicine.
Chicago/Turabian
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Vigneault, Annabelle, N. Mylniczenko, R. Arnold, Shanese L. Jasper-Trotter, Noémie M. Summa, Catherine Rousseau, and C. Vergneau-Grosset. “MANAGEMENT OF SUSPECTED DILATED CARDIOMYOPATHY WITH PIMOBENDAN IN TWO LEOPARD SHARKS (TRIAKIS SEMIFASCIATA).” Journal of zoo and wildlife medicine (2023).
MLA
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Vigneault, Annabelle, et al. “MANAGEMENT OF SUSPECTED DILATED CARDIOMYOPATHY WITH PIMOBENDAN IN TWO LEOPARD SHARKS (TRIAKIS SEMIFASCIATA).” Journal of Zoo and Wildlife Medicine, 2023.
BibTeX Click to copy
@article{annabelle2023a,
title = {MANAGEMENT OF SUSPECTED DILATED CARDIOMYOPATHY WITH PIMOBENDAN IN TWO LEOPARD SHARKS (TRIAKIS SEMIFASCIATA)},
year = {2023},
journal = {Journal of zoo and wildlife medicine},
author = {Vigneault, Annabelle and Mylniczenko, N. and Arnold, R. and Jasper-Trotter, Shanese L. and Summa, Noémie M. and Rousseau, Catherine and Vergneau-Grosset, C.}
}
Abstract: Two adult male leopard sharks (Triakis semifasciata) under managed care were diagnosed with suspected dilated cardiomyopathy. Clinical signs included lethargy, inappetence, and regurgitation. On cardiac ultrasound, fractional shortening was 14% and 10%, respectively (versus 21%–31% in four healthy conspecifics). Ventricular end-diastolic diameter to body weight ratio was 1.72 cm/kg in Case 1 (versus 0.52–1.24 cm/kg in four conspecifics). These results collectively suggested a dilated cardiomyopathy. Treatment was implemented with oral pimobendan at 0.3 mg/kg q48h for 1 mon. The pimobendan dose was increased to 0.5 mg/kg 3/wk, following plasmatic dosage of pimobendan and its metabolite. After 3 mon, fractional shortening increased to 38% and 20%, respectively, sharks regained a normal appetite, and body weight increased by 50% in one individual. After 2 yr, both individuals remained clinically normal, and no adverse effect was noted with pimobendan administration. Pimobendan plasma concentration suggested that this medication was well absorbed in this species.
